The billion dollar question

The billion dollar question – Brief Article

“The ultimate question may be, “Is any very preterm infant normal?’ Human development is slow relative to that of other species. The homeostatic physiologic adaptations are essential for survival of the preterm infant. The preterm infant is exposed for many weeks to high cortisol and thyroid hormone levels after preterm birth. (1) In experimental models these hormones disrupt normal development.”


(1.) Burrow GN, Fisher DA, Larsen PR. Maternal and fetal thyroid function. N Engl J Med. 1994;331:1072-1078


Jobe AH. Predictors of outcomes in preterm infants–which ones and when? J Pediatr. 2001;138:153-156

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COPYRIGHT 2002 American Academy of Pediatrics

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