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Research Initiative/Treatment Action!

Nursing assessment of the patient with primary HIV infection: key to improving clinical recognition

Nursing assessment of the patient with primary HIV infection: key to improving clinical recognition – Clinical Considerations Paul Simmons David is a 29-year-old Hispanic male who presents complaining of fatigue, headache, muscle aches, a sore throat, and nausea. Physical assessment demonstrates an erythematous maculopapular rash on the trunk and symmetric adenopathy. His temperature is 37.6 […]

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Research Initiative/Treatment Action!

Roundtable discussion

Roundtable discussion – HIV/AIDS research One of the objectives of the Basic Science Workshop is to “identify from the work presented the implications for activism.” In other words, how can advocates for people with H1V support the work of bench researchers? Although many are familiar with the work that activists do in HIV/AIDS-related social policy […]

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Research Initiative/Treatment Action!

About the Drug Fact Sheets

About the Drug Fact Sheets This issue’s drug fact sheets summarize the currently approved drugs indicated for the treatment of HIV infection. The drugs are grouped according to class: nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors. Within each class, the drugs are listed in the order of approval by […]

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Research Initiative/Treatment Action!

HIV drug resistance testing: data be damned

HIV drug resistance testing: data be damned HIV’s ability to develop drug resistance, through rapid turnover and high rates of mutation, has been the Achilles’ heel of antiretroviral therapy. On a molecular level, HIV’s mechanism of replication is error prone and given to genetic infidelity. But on a therapeutic level, haphazard viral reproduction is the […]

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Research Initiative/Treatment Action!

the example of smoking cessation

The potential of behavior-change interventions to improve the HIV/AIDS survivorship experience: the example of smoking cessation Damon J. Vidrine The concept of survivorship, generally defined as the physical, psychosocial, and economic impact of disease and treatment on an individual, is widely recognized as an important field of research. The focus on survivorship research is perhaps […]

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Research Initiative/Treatment Action!

Oral warts in HIV-infected individuals

Oral warts in HIV-infected individuals Sandra Felefli Oral diseases are common manifestations of HIV infection, with up to 90% of HIV-infected patients developing an oral lesion through the course of their HIV disease.[1] Oral candidiasis, aphthous-like ulcerations, periodontal infections, salivary gland diseases, various malignancies and numerous viral opportunistic infections have been described in the oral […]

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Research Initiative/Treatment Action!

Insomnia in HIV and its management: one clinician’s perspective

Insomnia in HIV and its management: one clinician’s perspective Zishan Samiuddin This article is a practical, precise and concise overview of my 7.5 years of experience treating a broad range of sleep problems in a heterogeneous group of HIV-infected individuals at the Thomas Street Clinic (TSC) in Houston. TSC is a community-based clinic that provides […]

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Research Initiative/Treatment Action!

Out of the laboratory and into the bathroom cabinet: designing and implementing clinical trials

Out of the laboratory and into the bathroom cabinet: designing and implementing clinical trials – Clinical Trials Paul Simmons Overview Once a drug candidate has been identified and undergone study in the laboratory and animals, it enters clinical trial, usually composed of 3 phases. Generally, as the drug candidate goes from phases 1 to 3, […]

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Research Initiative/Treatment Action!

the study of HIV infection without progression to AIDS

Long-term nonprogressors: the study of HIV infection without progression to AIDS Thomas Gegeny Although the past decade has seen great strides in the treatment of HIV, much about the virus remains obscure. Drug development to date has mainly followed from research characterizing the life cycle of HIV (for instance, targeting viral reverse transcriptase or protease […]

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Research Initiative/Treatment Action!

LAMIVUDINE

LAMIVUDINE – Epivir Lamivudine tablets are film-coated, white, and diamond-shaped with the dosage “150” imprinted on one side and “GX CJ7” on the other side. This drug is also available in a flavored solution or in combination with zidovudine in a tablet formulation called “Combivir.” “The discovery of lamivudine’s hepatitis-suppressing potential will likely provide Glaxo […]