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Journal of Drugs in Dermatology

Sulodexide shows promise in the treatment of oral erosive/ulcerative lichen planus – Washington Whispers

Sulodexide shows promise in the treatment of oral erosive/ulcerative lichen planus – Washington Whispers – Brief Article This open non-randomized trial compared the effect of heparinoid sulodexide systemically compared with topical cyclosporine on chronic oral erosive/ulcerative lichen planus. Sulodexide is composed of 80% heparin and 20% dermatan sulfate. Preliminary studies have shown that low molecular […]

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Journal of Drugs in Dermatology

Photodynamic therapy in dermatology: history and horizons

Photodynamic therapy in dermatology: history and horizons – Articles Amy Forman Taub Abstract Photodynamic therapy (PDT) uses a photosensitizer, light, and molecular oxygen to selectively kill cells. When localized in the target tissue, the photosensitizer is activated by light to produce oxygen intermediates that destroy target tissue cells. The easy access of skin to light-based […]

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Journal of Drugs in Dermatology

Rituximab with or without pixantrone in treating patients with indolent non-Hodgkin’s lymphoma

Rituximab with or without pixantrone in treating patients with indolent non-Hodgkin’s lymphoma – Clinical Trial Review Sponsored by: Novuspharma RATIONALE: Drugs used in chemotherapy such as pixantrone use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies such as rituximab can locate cancer cells and either kill them […]

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Journal of Drugs in Dermatology

Once-daily valacyclovir to reduce the risk of transmission of genital herpes

Once-daily valacyclovir to reduce the risk of transmission of genital herpes The authors set forth to prove that valacyclovir (a nucleoside analogue) suppresses shedding of HSV type 2 (HSV-2) on genital mucosal surfaces and may prevent sexual transmission of HSV. A total of 1484 immunocompetent, heterosexual, monogamous couples were chosen: one with clinically symptomatic genital […]

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Journal of Drugs in Dermatology

Peptide vaccination for patients at high risk for recurrent melanoma – Clinical Trial Review

Peptide vaccination for patients at high risk for recurrent melanoma – Clinical Trial Review – Brief Article This study is currently recruiting patients. Sponsored by National Cancer Institute (NCI) This study wiI1 examine the effectiveness and side effects of an experimental vaccine to prevent recurrence of melanoma; the vaccine will be mixed with an oil-based […]

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Journal of Drugs in Dermatology

Photodynamic therapy in treating patients with skin cancer

Photodynamic therapy in treating patients with skin cancer This study is currently recruiting patients. Sponsored by Roswell Park Cancer Institute Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. Photodynamic therapy using aminolevulinic acid cream may be effective in treating patients with skin cancer. This is […]

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Journal of Drugs in Dermatology

Benzoyl peroxide and clindamycin are the two most widely prescribed topical antimicrobials in the treatment of acne – Washington Whispers

Benzoyl peroxide and clindamycin are the two most widely prescribed topical antimicrobials in the treatment of acne – Washington Whispers – Brief Article BENZOYL PEROXIDE AND CLINDAMYCIN ARE THE TWO most widely prescribed topical antimicrobials in the treatment of acne. This study compared the antimicrobial efficacy, in vivo, of benzoyl peroxide and clindamycin against Propionibacterium […]

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Journal of Drugs in Dermatology

Early improvement in rhytides and skin laxity following treatment with a combination fractional laser emitting two wavelengths sequentially

Early improvement in rhytides and skin laxity following treatment with a combination fractional laser emitting two wavelengths sequentially K. Wade Foster Abstract Background: Carbon dioxide laser resurfacing remains the gold standard for the treatment of photoaged skin. Today, however, fewer patients will tolerate the postoperative downtime associated with the use of this device. Fractional photothermolysis […]

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Journal of Drugs in Dermatology

Their role in dermatology practice

Their role in dermatology practice – Focus On: Cosmeceuticals Neil S Sadick Introduction Cosmeceutical skin care products, which fall somewhere between cosmetics and pharmaceuticals, are playing an increasing role in the dermatologist’s daily practice (19). These agents contain active ingredients with known and documented biologic effects on the skin. Cosmeceutical sales represent the greatest growth […]

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Journal of Drugs in Dermatology

The new antihistamines—desloratadine and levocetirizine: a review

The new antihistamines—desloratadine and levocetirizine: a review Noah Scheinfeld Introduction Antihistamines are among the most commonly used medications by allergists and dermatologists worldwide. They are used to treat indications such as rhinitis, urticaria, seasonal allergies, and pruritus, and their potential role in treating the itch and rash of atopic dermatitis remains unclear. However, many antihistamines […]