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International Journal of Leprosy and Other Mycobacterial Diseases

A study of the reproducibility of two serological assays for detection of mycobacterium leprae infection

A study of the reproducibility of two serological assays for detection of mycobacterium leprae infection Parkash, Om TO THE EDITOR: The detection of Mycobacterium leprae infection is one of the important tools for effective control of leprosy. It is known that phenolic glycolipid-1 (PGL-1) and 35-kDa protein are the two components of M. leprae which […]

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International Journal of Leprosy and Other Mycobacterial Diseases

“Were-Wolf” Cutaneous Tuberculosis1, [dagger]

“Were-Wolf” Cutaneous Tuberculosis1, [dagger] Mahajan, Vikram K ABSTRACT Lupus vulgaris is a variant of cutaneous tuberculosis. Its more destructive and mutilating clinical forms have become rarer in consonance of a general decline of cutaneous tuberculosis. It is rarely seen now in developed countries due to stringent control measures, improved quality of living and effective therapeutic […]

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International Journal of Leprosy and Other Mycobacterial Diseases

A Comparison of Economic Aspects of Hospitalization Versus Ambulatory Care in the Management of Neuritis Occurring in Lepra Reaction1

A Comparison of Economic Aspects of Hospitalization Versus Ambulatory Care in the Management of Neuritis Occurring in Lepra Reaction1 N, Ravi H The economic aspects of the management of neuritis in leprosy have received scant attention. A recent paper by Naik and Ganapathy highlighted the need for such studies in the present declining phase of […]

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International Journal of Leprosy and Other Mycobacterial Diseases

Single Nucleotide Polymorphisms (SNPs) at -238 and -308 Positions in the TNF[alpha] Promoter: Clinical and Bacteriological Evaluation in Leprosy1

Single Nucleotide Polymorphisms (SNPs) at -238 and -308 Positions in the TNF[alpha] Promoter: Clinical and Bacteriological Evaluation in Leprosy1 Vanderborght, Patrícia R Leprosy, a chronic human disease, is the result of infection by Mycobacterium leprae. The clinical spectrum of the disease includes two polar (lepromatous-LL and tuberculoid-TT) and three borderline forms (tuberculoid-BT, borderline-BB, and lepromatous-BL) […]

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International Journal of Leprosy and Other Mycobacterial Diseases

Mechanisms Involved in Peripheral Nerve Damage in Leprosy with Special Reference to Insights Obtained from In Vitro Studies and the Experimental Mouse Model1

REVIEW: Mechanisms Involved in Peripheral Nerve Damage in Leprosy with Special Reference to Insights Obtained from In Vitro Studies and the Experimental Mouse Model1 Birdi, Tannaz J ABSTRACT The histopathological observations of Khanolkar and Iyer, that M. leprae has a predeliction for nerves, first highlighted the central role of peripheral nerves in the pathology of […]

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International Journal of Leprosy and Other Mycobacterial Diseases

Human T-cell responses to the RD1-encoded protein TB27.4 (Rv3878) from Mycobacterium tuberculosis

Human T-cell responses to the RD1-encoded protein TB27.4 (Rv3878) from Mycobacterium tuberculosis Agger, E. M., Brock, L, Okkels, L. M., Arend, S. M., Aagaard, C. S., Weldingh, K. N., and Andersen, P. Human T-cell responses to the RD1-encoded protein TB27.4 (Rv3878) from Mycobacterium tuberculosis. Immunology 110(4) 2003 507-512. In recent years, there has been considerable […]

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International Journal of Leprosy and Other Mycobacterial Diseases

Uveitis seen in the long clinical course of leprosy

Uveitis seen in the long clinical course of leprosy Namisato, Masako TO THE EDITOR: Frequent occurrence of the anterior uveitis (UV) in leprosy patients is a wellknown fact (1). However, we cannot find enough explanation for the details of these uveal inflammations. From our experiences in leprosy patients, most UV develops as chemotherapy is progressing […]

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International Journal of Leprosy and Other Mycobacterial Diseases

Sciatic nerve of normal and T200x5R Swiss white mice fails to support multiplication of intraneurally injected M. leprae

Sciatic nerve of normal and T200x5R Swiss white mice fails to support multiplication of intraneurally injected M. leprae Shetty, Vanaja P Sciatic Nerve of Normal and T200x5R Swiss White Mice Fails to Support Multiplication of Intraneurally Injected M. Ieprael Involvement of the peripheral nerve is the special and most important feature of leprosy in man. […]

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International Journal of Leprosy and Other Mycobacterial Diseases

Disseminated intravascular coagulopathy as an adverse reaction to intermittent rifampin schedule in the treatment of leprosy

Disseminated intravascular coagulopathy as an adverse reaction to intermittent rifampin schedule in the treatment of leprosy Souza, Cacilda S CLINICAL NOTES In an effort to increase the utility of the JOURNAL in continuing medical education, in this section we welcome contributions dealing with practical problems in leprosy work. Submissions to this section will undergo minimal […]

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International Journal of Leprosy and Other Mycobacterial Diseases

“Metabolic theory of leprosy”

“Metabolic theory of leprosy” Bergel, Meny TO THE EDITOR: I have read the commentary of the book Metabolic Theory of Leprosy (IJL 68;333, 2000). Almost the entire article deals with matters unrelated to the metabolic theory. Only three paragraphs refer to it, and in a wrong way: a) the paragraph “the treatment should consist in […]