CURRENT LITERATURE This department carries selected abstracts of articles published in current medical journals dealing with leprosy and other mycobacterial diseases. General and Historical Britton, W. J., and Lockwood, D. N. Leprosy. Lancet 363(9416) (2004) 1209-1219. Comment in: Lancet 363(9424) (2004) 1911. Leprosy remains an important health problem worldwide. The disease is caused by a […]
Category: International Journal of Leprosy and Other Mycobacterial Diseases
Effect of phorbol myristate acetate (PMA) and ionophore A23187 on interleukin-2 levels and proliferation of activated T lymphocytes from patients with lepromatous leprosy Fernando Alfaro-Bustamante Effect of Phorbol Myristate Acetate (PMA) and lonophore A23187 on Interleukin-2 Levels and Proliferation of Activated T Lymphocytes from Patients with Lepromatous Leprosy1 Fernando Alfaro-Bustamante, Gabriela Ramirez-Flores, Amado GonzalezMendoza, Alfonso […]
Long-term follow up of multibacillary leprosy patients with high BI treated with WHO/MDT regimen for a fixed duration of two years Shaw, Isaac Neeraj The World Health Organization (WHO), to overcome the problem of drug resistance and to introduce an effective and practicable regimen of finite duration, in 1982 recommended multidrug therapy (WHO/ MDT) for […]
Serum Butyrylcholinesterase Activity in Leprosy1 Suneetha, Lavanya M To THE EDITOR: Butyrylcholinesterase (BuChE) is a multifunctional enzyme (1, 8) mainly regulating cholinergic transmission, and is involved in growth, differentiation, and degeneration of nervous tissue (9). BuChE in the serum is a 90 kDa glycoprotein with three major subunits of approximately 50 kDa, 21 kDa and […]
Immunological reactions to mycobacterial proteins in the spectrum of leprosy Rada, Elsa Maria To THE EDITOR: Leprosy, still a public health probelm in many parts of the world, is a chronic mycobacterial disease produced by an intracellular parasite, Mycobacterium leprae, which multiplies mainly within tissue macrophages and Schwann cells in peripheral nerves. A good immunological […]
Daily multidrug therapy for leprosy; results of a fourteen-year experience Georges-Yves de Carsalade Daily Multidrug Therapy for Leprosy; Results of a Fourteen-Year Experience1 Georges-Yves de Carsalade, Daniel Wallach, Edith Spindler, Jean Pennec, Francois Cottenot and Beatrice Flageul2 In 1980, at the Saint-Louis Hospital in Paris, the main leprosy center in France, we started to treat […]
nose in leprosy: Immunohistology of the nasal mucosa, The Fokkens, Wytske J The Nose in Leprosy: Immunohistology of the Nasal Mucosa1 In 1874 Armauer Hansen described the causative organism of leprosy, the acid-fast bacterium Mycobacterium leprae (6). From that time onward, leprosy had to be considered an infectious disease. However, it has not been possible […]
Editorial: The paleoepidemiologyof leprosy: An overview Lechat, Michel F The Paleoepidemiology of Leprosy: an Overview* Introduction: paleoepidemiology and the ecology of diseases The paleoepidemiology of an infectious disease should ideally start by tracing its origin, that is, the prime encounter of man with the germ, its reservoirs and its vectors, in a long-vanished ecology. Next, […]
The anti-leprosy campaign in Colombia: the rhetoric of hygiene and science, 1920-1940 Obregon, D. The anti-leprosy campaign in Colombia: the rhetoric of hygiene and science, 1920-1940. Hist. Cienc. Saude Manguinhos. 10(Suppl 1) (2003) 179-207. Since the 1920’s, the medical community realized that the strategy of leprosy control based on segregation and persecution of patients was […]
Effectiveness of bacillus Calmette-Guerin (BCG) vaccination in the prevention of leprosy; a case-finding control study in Nagpur, India Zodpey, Sanjay P Effectiveness of Bacillus Calmette-Guerin (BCG) Vaccination in the Prevention of Leprosy; A Case-Finding Control Study in Nagpur, India1 The effect of the bacillus Calmette Guerin (BCG) vaccine on mycobacterial diseases is still controversial despite […]