Categories
Indian Journal of Pharmacology

Experimental animal models to induce cardiac arrhythmias

Experimental animal models to induce cardiac arrhythmias L. Bhatt Byline: L. Bhatt, K. Nandakumar, S. Bodhankar Cardiac arrhythmias are of different types based on their mechanism and origin. The information gathered from animal studies has been instrumental in devising diagnostic and therapeutic strategies; so different animal models are needed for different types of arrhythmias. The […]

Categories
Indian Journal of Pharmacology

Hypolipidemic and antioxidant activities of Asparagus racemosus in hypercholesteremic rats

Hypolipidemic and antioxidant activities of Asparagus racemosus in hypercholesteremic rats N. Visavadiya Byline: N. Visavadiya, A. R.L. Narasimhacharya OBJECTIVE: To study the efficacy of Asparagus racemosus in reducing the cholesterol levels and as an antioxidant in hypercholesteremic rats. MATERIALS AND METHODS: Hypercholesteremia was induced in normal rats by including 0.75 g% cholesterol and 1.5 g% […]

Categories
Indian Journal of Pharmacology

Evaluation of antidepressant-like activity of glycyrrhizin in mice

Evaluation of antidepressant-like activity of glycyrrhizin in mice Dinesh Dhingra Byline: Dinesh. Dhingra, Amandeep. Sharma OBJECTIVE: To investigate the antidepressant-like effect of glycyrrhizin (glycyrrhizic acid ammonium) in mice. MATERIALS AND METHODS: Glycyrrhizin (1.5, 3.0 and 6.0 mg/kg, i.p.) was administered once daily for seven successive days to separate groups of young male Swiss albino mice. […]

Categories
Indian Journal of Pharmacology

A new strategy to raise HDL cholesterol levels

Torcetrapib: A new strategy to raise HDL cholesterol levels Reena Bhardwaj Byline: Reena. Bhardwaj, P. Bhardwaj Statins are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase. They reduce low-density lipoprotein (LDL) cholesterol levels and hence they are use to reduce the risk of coronary heart disease. However, many of the cardiovascular events are not prevented by statin […]

Categories
Indian Journal of Pharmacology

Effect of folate treatment on homocysteinemia in cardiac patients: A prospective study

Effect of folate treatment on homocysteinemia in cardiac patients: A prospective study K. Mehta Byline: K. Mehta, M. Chag, K. Parikh, U. Shah, H. Baxi, A. Chandarana, A. Naik, Ramesh. Goyal OBJECTIVE: To study the effect of folate treatment on homocysteine (HCY) levels in patients with Coronary Artery Disease (CAD). We also made an attempt […]