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Applied Genetics News

Down’s Syndrome Stem Cells Studied

Down’s Syndrome Stem Cells Studied Writing in the recent issue (January 26, 2002) of the British medical journal The Lancet, a team of scientists from the University of Cambridge, University College London, and the University of Wisconsin-Madison report findings from a genetic study based on stem cells derived from Down’s syndrome compared with normal fetal […]

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Applied Genetics News

Growing Interest in Microarrays

Growing Interest in Microarrays A joint venture between Molecular Dynamics (880 E. Arques Ave., Sunnyvale, CA 94086; Tel: 408/737-3000) and Amersham Pharmacia Biotech (800 Centennial Ave., Piscataway, NJ 08855-1327; Tel: 908/457-8000, Fax: 908/457-0557) has received the support of Bristol-Myers Squibb (BMS, 345 Park Ave., New York, NY 10154-0037; Tel: 212/546-4000) as well as American Home […]

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Applied Genetics News

CLONING: Bringing Back Endangered Species

CLONING: Bringing Back Endangered Species The first successful cloning of an endangered animal to late-stage fetal development has been reported. Advanced Cell Technology’s (ACT, One Innovation Dr., Worcester, MA 01650; Tel: 508/756-1212, Fax: 508/756-0931; Website: www.advancedcell.com) cross-species nuclear transfer to clone the endangered gaur used eggs derived from cows. In late November, a domestic cow […]

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Applied Genetics News

Altered CD4+ Cells Engraft into Marrow

Altered CD4+ Cells Engraft into Marrow Enzo Biochem, Inc. (60 Executive Blvd., Farmingdale, NY 11735; Tel: 516/755-5500, Fax: 516/755-5569) has reported new data on the first individual treated in the Phase I clinical trial of HGTV-43. The company’s HIV-1 gene medicine product shows that after nine- and-one-half-months, Enzo-engineered cells have successfully engrafted in the patient’s […]

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Applied Genetics News

Infectious Disease Grants Awarded

Infectious Disease Grants Awarded Initial awards have been announced to fund 12 research projects under a new joint NIH-NSF Ecology of Infectious Diseases initiative. The initiative supports efforts to understand the underlying ecological and biological mechanisms that govern relationships between human-induced environmental changes and the emergence and transmission of infectious diseases. The grants are funded […]

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Applied Genetics News

Angiozyme in Clinical Trials

Angiozyme in Clinical Trials Ribozyme Pharmaceuticals, Inc. (RPI, 2950 Wilderness Place, Boulder, CO 80301; Tel 303/449-6500, Fax: 303/449-6995) and Chiron Corp. (4560 Horton St., Emeryville, CA 94608; Tel: 510/655-8730, Fax: 510/665-9910, Website: www.chiron.com) have completed phase Ia and Ib trials of their anti-angiogenic compound, Angiozyme. Angiozyme is a ribozyme compound, the first to enter clinical […]

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Applied Genetics News

Igen Wins Injunction Against Boehringer

Igen Wins Injunction Against Boehringer Igen International (1530 E. Jefferson St., Rockville, MD 20852; Tel: 301/984-8000, Fax: 301/230-0158) reports that the U.S. District Court for the District of Maryland, Southern Division granted Igen’s motion for a preliminary injunction precluding Boehringer Mannheim from distributing products based on Igen’s proprietary “Origen” technology to physicians’ offices, including physicians’ […]

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Applied Genetics News

Blocking Telomerase Remortalizes Cancer Cells

Blocking Telomerase Remortalizes Cancer Cells – Brief Article B.-S. Herbert, A. E. Pitts, and colleagues at the University of Texas Southwestern Medical Center (5323 Harry Hines Blvd., Dallas, TX 75235) have shown that inhibitors of telomerase can remortalize transformed human breast epithelial cells and human prostate cancer cells in culture, ultimately leading to their cell […]

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Applied Genetics News

Rare T-Cell Involved in Wound Repair

Rare T-Cell Involved in Wound Repair Researchers at The Scripps Research Institute (TSRI) (10550 N. Torrey Pines Rd., La Jolla, CA; Tel: 858/784-1000) led by Wendy Havran have identified a major role in promoting wound repair played by the little-known gamma-delta T cell that resides mainly in the skin and the gut. The findings, published […]

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Applied Genetics News

ANTIBODIES: Yeast Library Patents Issued

ANTIBODIES: Yeast Library Patents Issued Genetastix Corp. (780 Montague Expressway, Suite 303, San Jose, CA 95131; Tel: 408/435-8900, Fax: 408/433-9288; Website: genetastix.com) has been granted two U.S. patents, U.S. Patent 6,410,271, issued on June 25, 2002, entitled “Generation of Highly Diverse Library of Expression Vectors Via Homologous Recombination in Yeast” and U.S. Patent 6,410,246, also […]