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Pure and Applied Chemistry

Use of sultines in the asymmetric synthesis of polypropionate antibiotics

Use of sultines in the asymmetric synthesis of polypropionate antibiotics Pierre Vogel Laboratory of Glycochemistry and Asymmetric Synthesis (LGSA), Swiss Federal Institute of Technology (EPFL), Batochime, CH-1015 Lausanne, Switzerland Abstract: At low temperature and in the presence of an acid catalyst, S[O.sub.2] adds to 1,3-dienes equilibrating with the corresponding 3,6-dihydro-1,2-oxathiin-2-oxides (sultines). These compounds are unstable […]